Thursday, March 19, 2009

Beauty is an equal opportunity now


With the ability to teach our skin to be young again, imagine a "chemical messenger" that can enter our skin cells and do just that. Our complexion will be left young and flawless as pigmentation and superficial blemishes reverse themselves. Now, a stem cell protein extract that is able to deliver just that is being offered by The Biogenesis Clinique. The extract is called AAPE.

Able to give rise to all of the different tissues of the human body, stem cells have the unique characteristic of "plasticity". Two distinguishing characteristics separate stem cells from all others: They can differentiate into many cell types with specific functions and they are unspecialized, in that they can clone themselves without limit.

More than any other tissue in the body, human adipose (fat) tissue has the highest concentration of adult stem cells. This was recently established by scientists. When comparing to bone marrow, a given volume of adipose tissue contains 1,000 times more stem cells. 200 millions stem cells can be derived from just 500 mL of fat.

Stem cells have many unique applications in science and medicine, but this is the first time, protein extract derived from stem cells are used in the field of cosmetic dermatology.

Biogenesis Clinique has introduced facial rejuvenation and strech mark therapies using AAPE. It is a mixture of refined growth factor proteins that is extracted from human adipose-derived stem cells. AAPE (advanced adipose-derived stem cell protein extract) uses proteins or chemical messengers that are extracted from stem cells found in human fat tissue. These messengers send a signal to cells in the skin teaching them to regenerate when deposited or absorbed into the skin.

"Let's regenerate and be young againI" The AAPE cells are extracted from human adipocytes (fat cells) during the process of lipoaspiration (fat suction) and they contain the maximal number of stem cells in the human body. By cultivating these regenerative cells in test-tubes, they can establish cell lines which will serve as a reservoir of stem cells for anti-aging and aesthetic therapies far superior than traditional methods of synthetic chemicals.

The innate ability to rearrange, change, or repair local tissues significantly and rapidly is held by the AAPE protein messengers extracted from these stem cells. Correcting facial fat atrophy may be one of the most promising applications for AAPE since it can regenerate the fat that is lost through the natural aging process. AAPE could possibly rejuvenate the face by regenerating the skin from the inside out as well as replace lost facial volume.

Effects can be seen after one sessions. Nevertheless, 3 sessions are required for optimum results, with each session consisting of multiple tiny punctures using microneedling method, a process which takes about 60 minutes. For long lasting anti-aging effects a series of six sessions are typically performed to initially prime the skin.


The CTFA (Cosmetic Toiletry and Fragrance Association) approved AAPE as a cosmetic ingredient on September 13th, 2006. It is a growth factor that is derived from human fat stem cells. It has also been registered with INCI as human adipocyte conditioned media extract. This product is patented. (Patent registration number: PCT/KR2006/004111).

The procedure for the face costs about $600 USD per session.

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